SCHEMBL6941841

SCHEMBL6941841

CC(=O)Oc1ccc(C(C)C2=CC(=O)NC2=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
KDM4E B2RXH2 3/20 0.39
CYP3A4 P08684 2/20 0.39
ABCB11 O95342 1/20 0.39
ESR1 P03372 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
PDE4A P27815 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRK1 P41145 1/20 0.39
STAT6 P42226 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HIF1A Q16665 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
MAPT P10636 5/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
ELANE P08246 3/20 0.37
GLA P06280 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23797140 0.79 ESR1 (0.50) LMNAKDM4ECYP3A4ESR1CYP2C9
SCHEMBL9506851 0.78 LMNA (0.59) LMNAKDM4ECYP3A4ABCB11ESR1
SCHEMBL8871733 0.75 DAO (0.41) LMNAKDM4ECYP3A4ADRA2AHIF1A
SCHEMBL5422952 0.73 HSD17B10 (0.47) LMNAKDM4ECYP3A4TSHRMAPT
SCHEMBL13595800 0.72 ESR1 (0.59) LMNAKDM4ECYP3A4ABCB11ESR1
SCHEMBL14242097 0.72 ESR1 (0.59) LMNAKDM4ECYP3A4ABCB11ESR1
SCHEMBL3173595 0.72 TSHR (0.37) TSHRMEN1KMT2A
SCHEMBL28927408 0.72 ELANE (0.59) LMNAKDM4ECYP3A4ABCB11ESR1
SCHEMBL12021697 0.72 LMNA (0.52) LMNAKDM4ECYP3A4ABCB11ESR1
SCHEMBL1714626 0.70 LMNA (0.59) LMNAKDM4ECYP3A4ABCB11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569972-B1 Photo-alignment materials for liquid crystal alignment film SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-05-27 US disclosed
EP-1281746-A2 Photo-alignment materials for liquid crystal alignment film SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-02-05 EP disclosed