SCHEMBL3173595

SCHEMBL3173595

CC(=O)OC(C)C1=CC(=O)NC1=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
HRH1 P35367 1/20 0.33
KMT2A Q03164 1/20 0.33
GLS2 Q9UI32 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28178938 0.82 TSHR (0.33) TSHR
Acetic Acid SCHEMBL28734535 0.74
SCHEMBL1425299 0.73 PTGS2 (0.33) TSHR
SCHEMBL6941841 0.72 LMNA (0.41) TSHRMEN1KMT2A
Ammonia Solution, Strong SCHEMBL27921266 0.71 EEF2K (0.37)
Hydrochloric Acid SCHEMBL28287132 0.68 GABRP (0.32)
SCHEMBL9562487 0.68
SCHEMBL10446702 0.67 PLK1 (0.57) TSHRMEN1KMT2AGLS2
SCHEMBL17924852 0.66 MAOA (0.33)
SCHEMBL17924867 0.64 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051665-B1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME ALBEMARLE CORP (US) 2006-07-12 EP claimed
US-7649027-B2 having juts via photopolymerization in supercritical carbon dioxide; calcining KANSAI PAINT CO., LTD. (JP) 2010-01-19 US disclosed
US-20090023830-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2009-01-22 US disclosed
EP-1698647-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2006-09-06 EP disclosed
US-7081486-B2 Method of producing polymer SHIZUOKA UNIVERSITY (JP) 2006-07-25 US disclosed
EP-1598374-A1 METHOD OF PRODUCING POLYMER Japan as represented by President of Shizuoka University (JP) 2005-11-23 EP disclosed
US-20050143481-A1 Method of producing polymer KANSAI PAINT CO., LTD. (JP) 2005-06-30 US disclosed
WO-2000020517-A2 RADIATION-CURABLE COMPOSITIONS COMPRISING MALEIMIDE COMPOUNDS AND METHOD FOR PRODUCING A SUBSTRATE WITH A CURED LAYER DSM N.V. (NL) 2000-04-13 WO disclosed