Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047162 | 0.83 | L3MBTL1 (0.54) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL1444225 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1ADRB2ADRB1MAPT | |
| SCHEMBL817445 | 0.80 | TSHR (0.60) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL16414613 | 0.80 | TSHR (0.60) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL16414719 | 0.80 | TSHR (0.60) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL7774040 | 0.80 | L3MBTL1 (0.50) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL7952233 | 0.79 | SCN1A (0.50) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL11613592 | 0.79 | KDM4E (0.49) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL5575173 | 0.79 | KDM4E (0.49) | KDM4EGAAALDH1A1MAOBAOC3 | |
| SCHEMBL773252 | 0.79 | MAOB (0.55) | KDM4EGAAALDH1A1MAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |