Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790851 | 0.87 | CTSL (0.71) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL3927028 | 0.87 | CTSL (0.71) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL6946429 | 0.84 | CAPN1 (0.55) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL7308097 | 0.84 | CAPN1 (0.55) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL14316003 | 0.84 | L3MBTL1 (0.51) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL6941033 | 0.83 | CA12 (0.55) | GAARAB9ASMN1; SMN2 | |
| SCHEMBL8696650 | 0.83 | CTSL (0.60) | CTSLCTSSCTSKALDH1A1TACR1 | |
| SCHEMBL12518333 | 0.82 | CDYL2 (0.49) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL1793176 | 0.81 | GAA (0.76) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL31206887 | 0.81 | GAA (0.76) | GAARAB9ACTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944582-B1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0944582-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025883-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |