Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445983 | 0.79 | PDK2 (0.33) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL9663491 | 0.75 | SLC6A4 (0.36) | SLC6A4SLC6A3CYP3A4THRBMAP3K14 | |
| SCHEMBL8871790 | 0.71 | SLC6A4 (0.36) | SLC6A4SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL9835436 | 0.70 | SLC6A4 (0.43) | SLC6A4SLC6A3CYP3A4THRBMAP3K14 | |
| SCHEMBL6940427 | 0.69 | SLC6A3 (0.37) | SLC6A4SLC6A3CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL9835917 | 0.68 | SLC6A4 (0.41) | SLC6A4SLC6A3CYP3A4THRBMAP3K14 | |
| SCHEMBL10361370 | 0.68 | SLC6A3 (0.38) | SLC6A4SLC6A3CYP3A4THRBMAP3K14 | |
| SCHEMBL2171978 | 0.68 | SLC6A4 (0.42) | SLC6A4SLC6A3CYP3A4THRBALDH1A1 | |
| SCHEMBL9662300 | 0.68 | CYP3A4 (0.39) | SLC6A4SLC6A3CYP3A4THRBMAP3K14 | |
| SCHEMBL2662444 | 0.66 | SLC6A4 (0.41) | SLC6A4SLC6A3CYP3A4MAP3K14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927719-B1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6204415-B1 | 2,2-DIFLUORO-2-ETHYLTHIOACETOPHENONE DERIVATIVES OF GIVEN FORMULA WHICH HAVE USE AS INTERMEDIATES TO ANTIMYCOTIC AGENTS | SSP CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-6194592-B1 | AS ANTIMYCOTIC AGENT | SSP CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6083968-A | A FUNGICIDE; 1,1-DIFLUORO-1-ETHYL THIENYL OR ETHYL THIENYL OXIDES-2-(2,4-SUBSTITUTED PHENYL)-3-(1H-1,2,4-TRIA ZOL-1-YL)-2-OXY OR HYDROXY COMPOUND | SSP CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0927719-A1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |