SCHEMBL7568090

SCHEMBL7568090

CCOC(=O)c1nn(-c2ccc(NC(=O)Cc3cc(C(=N)N)ccc3O)cc2C)c2c1CCC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
LMNA P02545 5/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ADRB2 P07550 1/20 0.39
F10 P00742 2/20 0.36
PRSS1 P07477 1/20 0.36
ANO1 Q5XXA6 2/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
F2 P00734 2/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
TP53 P04637 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
POLB P06746 1/20 0.34
PLAU P00749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7071483 0.99 MAPT (0.38) MAPTLMNAKMT2AMEN1SMN1; SMN2
Hydrochloric Acid SCHEMBL7074489 0.88 MAPT (0.37) MAPTLMNAKMT2AMEN1F10
SCHEMBL7562213 0.85 MAPT (0.35) MAPTLMNAKMT2AMEN1F10
Hydrochloric Acid SCHEMBL7562852 0.84 MAPT (0.34) MAPTKMT2AMEN1F10PRSS1
SCHEMBL6942538 0.79 KDR (0.42) MAPTF10PRSS1F2TP53
SCHEMBL6937674 0.77 MAPT (0.37) MAPTLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL6941666 0.77 F10 (0.39) MAPTLMNAKMT2AMEN1F10
Hydrochloric Acid SCHEMBL7561132 0.76 F10 (0.38) MAPTLMNAKMT2AMEN1F10
Hydrochloric Acid SCHEMBL7069690 0.76 MAPT (0.37) MAPTLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL6937124 0.74 F10 (0.37) MAPTLMNAKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US claimed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 MAPT 4388/4885LMNA 1079/4885KMT2A 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.