Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942565 | 1.00 | RORC (0.41) | RORCMMP9BDKRB2BDKRB1MMP1 | |
| SCHEMBL6941442 | 0.90 | RORC (0.40) | RORCMMP9BDKRB2BDKRB1MMP1 | |
| SCHEMBL6936904 | 0.90 | RORC (0.40) | RORCMMP9BDKRB2BDKRB1MMP1 | |
| SCHEMBL6936907 | 0.90 | RORC (0.40) | RORCMMP9BDKRB2BDKRB1MMP1 | |
| SCHEMBL7648412 | 0.89 | MMP9 (0.42) | RORCMMP9BDKRB2BDKRB1 | |
| SCHEMBL7648416 | 0.89 | MMP9 (0.42) | RORCMMP9BDKRB2BDKRB1 | |
| SCHEMBL6945975 | 0.87 | MMP9 (0.41) | RORCMMP9BDKRB2BDKRB1 | |
| SCHEMBL6945183 | 0.87 | MMP9 (0.43) | RORCMMP9MMP1MMP3MMP7 | |
| SCHEMBL6945180 | 0.87 | MMP9 (0.43) | RORCMMP9MMP1MMP3MMP7 | |
| SCHEMBL6945980 | 0.87 | MMP9 (0.41) | RORCMMP9BDKRB2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155013-B1 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2003-07-23 | — | — | EP | disclosed |
| US-6479515-B1 | FOR THE TREATMENT OF PAIN AND INFLAMMATION, AND ESPECIALLY IN THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-11-12 | — | — | US | disclosed |