Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 17/20 | 0.40 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945980 | 1.00 | MMP9 (0.41) | MMP9RORCBDKRB2BDKRB1HCRTR1 | |
| SCHEMBL7648412 | 0.91 | MMP9 (0.42) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL7648416 | 0.91 | MMP9 (0.42) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL6945183 | 0.89 | MMP9 (0.43) | MMP9RORC | |
| SCHEMBL6945180 | 0.89 | MMP9 (0.43) | MMP9RORC | |
| SCHEMBL6936907 | 0.89 | RORC (0.40) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL6941442 | 0.89 | RORC (0.40) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL6936904 | 0.89 | RORC (0.40) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL6942565 | 0.87 | RORC (0.41) | MMP9RORCBDKRB2BDKRB1 | |
| SCHEMBL6942563 | 0.87 | RORC (0.41) | MMP9RORCBDKRB2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155013-B1 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2003-07-23 | — | — | EP | disclosed |
| US-6479515-B1 | FOR THE TREATMENT OF PAIN AND INFLAMMATION, AND ESPECIALLY IN THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-11-12 | — | — | US | disclosed |
| WO-2000050418-A9 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-02-22 | — | — | WO | disclosed |