Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663878 | 0.92 | OPRM1 (0.47) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4663732 | 0.87 | HDAC4 (0.38) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4663713 | 0.86 | HDAC4 (0.38) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4663621 | 0.84 | OPRM1 (0.49) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL6938405 | 0.84 | LMNA (0.36) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL150889 | 0.84 | OPRK1 (0.57) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL150888 | 0.84 | OPRK1 (0.57) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4663634 | 0.83 | OPRM1 (0.49) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4663727 | 0.83 | OPRM1 (0.41) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 | |
| SCHEMBL4665507 | 0.82 | SMN1; SMN2 (0.51) | OPRM1SLC6A2SLC6A4OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368299-A2 | SUBSTITUTED C-CYCLOHEXYLMETHYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2003-12-10 | — | — | EP | claimed |
| WO-2002030870-A2 | SUBSTITUTED C-CYCLOHEXYLMETHYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | claimed |