Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826874 | 0.67 | ALDH1A1 (0.43) | PARP1ALOX5ALDH1A1GAAKDM4E | |
| SCHEMBL27140846 | 0.66 | PARP1 (0.42) | PARP1ALOX5ALDH1A1GAAPIM1 | |
| SCHEMBL27141430 | 0.66 | PARP1 (0.49) | PARP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL24879793 | 0.66 | PARP1 (0.42) | PARP1ALOX5ALDH1A1GAAPIM1 | |
| SCHEMBL12241454 | 0.63 | ALDH1A1 (0.56) | PARP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20153300 | 0.62 | — | — | |
| SCHEMBL14663692 | 0.61 | ADORA3 (0.42) | PARP1ALDH1A1ADORA3MEN1KMT2A | |
| SCHEMBL24880333 | 0.61 | PARP1 (0.38) | PARP1ALOX5ALDH1A1GAAPIM1 | |
| SCHEMBL890356 | 0.61 | HTR2C (0.33) | PARP1 | |
| SCHEMBL13589780 | 0.58 | ALDH1A1 (0.50) | PARP1ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104391-A2 | ANTIBACTERIAL TARGETS IN ALLOIOCOCCUS OTITIDIS | WYETH HOLDINGS CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |
| US-6589738-B1 | Expressing a sublethal level of an antisense nucleic acid complementary to a nucleic acid encoding said gene to reduce its activity; drug screening; antibiotics | ELITRA PHARMACEUTICALS, INC. | 2003-07-08 | — | — | US | disclosed |