Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879783 | 0.68 | PARP1 (0.37) | NNMTPARP10PARP11PARP1PDPK1 | |
| SCHEMBL23031254 | 0.67 | MEN1 (0.33) | CRBN | |
| SCHEMBL13941528 | 0.66 | — | — | |
| SCHEMBL18870772 | 0.64 | GRM5 (0.31) | — | |
| SCHEMBL279310 | 0.62 | UHRF1 (0.43) | HTR2CNNMTPARP10PARP11PARP1 | |
| SCHEMBL22216146 | 0.61 | DRD4 (0.42) | HTR2CPARP10PARP11PARP1PDPK1 | |
| SCHEMBL6943002 | 0.61 | PARP1 (0.41) | PARP1 | |
| SCHEMBL13355386 | 0.60 | NNMT (0.38) | HTR2CNNMTEHMT2PARP10PARP11 | |
| SCHEMBL14222761 | 0.60 | MAOA (0.37) | HTR2CEHMT2 | |
| SCHEMBL18612816 | 0.59 | DRD4 (0.41) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |