SCHEMBL6943096

SCHEMBL6943096

C[Si](C)(C)c1cccc(Br)c1[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20819712 0.85 ALDH1A1 (0.39) ALDH1A1
SCHEMBL3110894 0.82 IDO1 (0.41) IDO1
SCHEMBL15612602 0.78 IDO1 (0.36) IDO1ALDH1A1
SCHEMBL31168893 0.77 ALDH1A1 (0.43) IDO1ALDH1A1
SCHEMBL3761218 0.77 ALDH1A1 (0.43) IDO1ALDH1A1
SCHEMBL24125843 0.74 HSD11B1 (0.38) ALDH1A1
SCHEMBL2636253 0.74 MAOB (0.33) ALDH1A1
SCHEMBL2783138 0.74 IDO1 (0.34) IDO1ALDH1A1
SCHEMBL31283290 0.74 MAOB (0.33) ALDH1A1
SCHEMBL5558831 0.74 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157047-B1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORP NORTH AMERICA INC (US) 2003-04-23 EP disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed