Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435095 | 0.91 | ITGA4 (0.53) | ITGA4ITGB1SMN1; SMN2 | |
| SCHEMBL7207127 | 0.88 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL14037387 | 0.87 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL1312192 | 0.87 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL1312190 | 0.87 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL7215569 | 0.85 | ITGA4 (0.52) | ITGA4ITGB1SMN1; SMN2 | |
| SCHEMBL3722480 | 0.84 | ITGA4 (0.67) | ITGA4ITGB1 | |
| SCHEMBL3722481 | 0.84 | ITGA4 (0.67) | ITGA4ITGB1 | |
| SCHEMBL7260591 | 0.83 | ITGA4 (0.54) | ITGA4ITGB1 | |
| SCHEMBL3499309 | 0.82 | NR1H4 (0.58) | ITGA4ITGB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534513-B1 | Antiinflammatory agents and fibronectins | CELLTECH R&D LIMITED (GB) | 2003-03-18 | — | — | US | disclosed |
| EP-1206463-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1206465-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1206463-A1 | FATTY ACID SYNTHASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1206465-A1 | FATTY ACID SYNTHASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014364-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001014362-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-01 | — | — | WO | disclosed |