Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207127 | 0.95 | ITGA4 (0.55) | ITGA4ITGB1LMNAL3MBTL1MMP8 | |
| SCHEMBL5719932 | 0.88 | ITGA4 (0.50) | ITGA4ITGB1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5719938 | 0.88 | ITGA4 (0.50) | ITGA4ITGB1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6943255 | 0.85 | ITGA4 (0.58) | ITGA4ITGB1SMN1; SMN2 | |
| SCHEMBL7260591 | 0.82 | ITGA4 (0.54) | ITGA4ITGB1PPARA | |
| SCHEMBL7098063 | 0.82 | ITGA4 (0.48) | ITGA4ITGB1 | |
| SCHEMBL9493387 | 0.81 | L3MBTL1 (0.67) | LMNAL3MBTL1MMP8PPARA | |
| SCHEMBL5719575 | 0.79 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL6561273 | 0.79 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL15707904 | 0.78 | LMNA (0.62) | LMNAL3MBTL1MMP8PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559179-B1 | Tinvention relates to the use of compounds as inhibitors of the fatty acid synthase FabH. | SMITHKLINE BEECHAM CORPORATION | 2003-05-06 | — | — | US | disclosed |