Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561273 | 0.84 | ITGA4 (0.55) | ITGA4ITGB1PPARGLTA4H | |
| SCHEMBL5719575 | 0.84 | ITGA4 (0.55) | ITGA4ITGB1PPARGLTA4H | |
| SCHEMBL6943255 | 0.83 | ITGA4 (0.58) | ITGA4ITGB1 | |
| Hydrochloric Acid SCHEMBL6509920 | 0.83 | ITGA4 (0.54) | ITGA4ITGB1PPARGLTA4H | |
| SCHEMBL7266529 | 0.82 | ITGA4 (0.50) | ITGA4ITGB1PPARGPPARDPPARA | |
| SCHEMBL7215569 | 0.82 | ITGA4 (0.52) | ITGA4ITGB1PPARA | |
| SCHEMBL7207127 | 0.81 | ITGA4 (0.55) | ITGA4ITGB1PPARA | |
| SCHEMBL23387525 | 0.77 | ITGA4 (0.48) | ITGA4ITGB1LTA4H | |
| SCHEMBL31070921 | 0.77 | ITGA4 (0.48) | ITGA4ITGB1LTA4H | |
| SCHEMBL15105296 | 0.77 | ITGA4 (0.48) | ITGA4ITGB1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534513-B1 | Antiinflammatory agents and fibronectins | CELLTECH R&D LIMITED (GB) | 2003-03-18 | — | — | US | disclosed |