Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | FBP1 | P09467 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943381 | 1.00 | HDAC2 (0.53) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL628779 | 0.92 | ALDH1A1 (0.54) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL1819167 | 0.92 | ALDH1A1 (0.54) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL9971655 | 0.87 | HDAC2 (0.58) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL18921375 | 0.86 | FBP1 (0.49) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL18921374 | 0.86 | FBP1 (0.49) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL29966035 | 0.80 | FBP1 (0.50) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL11329021 | 0.79 | MAOB (0.61) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| SCHEMBL11329024 | 0.79 | MAOB (0.61) | HDAC2FBP1ALDH1A1MAPTKDM4E | |
| Benzonitrile SCHEMBL8349605 | 0.79 | APP (0.59) | FBP1ALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083175-B1 | Triazole derivatives having antifungal activity | SANKYO CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6392082-B1 | CHEMICAL INTERMEDIATE | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6391903-B1 | THERAPY FOR FUNGI INFECTIONS | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6337403-B1 | CRYSTALLINE FORM OF A PHARMACEUTICAL COMPOSITION CONTAINING SAID DERIVATIVES WITH TREATING AND PREVENTING FUNGAL INFECTIONS USING BUTADIENE FLUORO BENZONITRILE GROUPS | SANKYO COMPANY, LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1083175-A2 | Triazole derivatives having antifungal activity | Sankyo Company Limited (JP) | 2001-03-14 | — | — | EP | disclosed |