Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533429 | 0.85 | CYP2C9 (0.65) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL13477518 | 0.84 | KMT2A (0.61) | NPC1SMN1; SMN2KMT2ARAB9APTPN1 | |
| SCHEMBL12466491 | 0.83 | CYP1A2 (0.55) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL8602062 | 0.83 | CYP2C9 (0.59) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL28038698 | 0.82 | NPC1 (0.51) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL17979590 | 0.82 | NPC1 (0.59) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3662909 | 0.81 | SMN1; SMN2 (0.71) | NPC1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL23928122 | 0.81 | CNR1 (0.49) | NPC1CYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL21153099 | 0.81 | TSHR (0.57) | NPC1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13024408 | 0.81 | TPSAB1 (0.47) | NPC1KMT2AMEN1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306732-B | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-113683622-B | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119306732-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119241554-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119219654-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-110312730-B | Cytotoxins and conjugates, uses thereof and methods of preparation | 四川科伦博泰生物医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
| EP-2421849-A1 | DIAMIDE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Theravance, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123766-A1 | DIAMIDE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND β2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | THERAVANCE, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | CD2, HAVCR2, CD4 | NPC1 2004/4885CYP1A2 4296/4885CYP2D6 2005/4885 |
| US-20060223826-A1 | Indole derivatives as somatostatin agonists or antagonists | SSTR1, SSTR3, NPY1R | NPC1 2308/4885CYP1A2 1259/4885CYP2D6 1673/4885 |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | CD2, HAVCR2, CD4 | NPC1 2004/4885CYP1A2 4296/4885CYP2D6 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.