Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153919 | 0.86 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL5510977 | 0.78 | TRPV1 (0.46) | P2RX7 | |
| SCHEMBL4509232 | 0.75 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL25120814 | 0.74 | DHPS (0.57) | — | |
| SCHEMBL4865366 | 0.74 | MAPK1 (0.56) | — | |
| SCHEMBL6939819 | 0.74 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL6939822 | 0.74 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL6940565 | 0.74 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL4508579 | 0.74 | MEN1 (0.61) | P2RX7 | |
| SCHEMBL2998509 | 0.74 | P2RX7 (0.59) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | claimed |
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | disclosed |
| US-6242470-B1 | RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS, ANTIALLERGENS; IRRITABLE BOWEL SYNDROME; AMIDATION | ASTRAZENECA AB (SE) | 2001-06-05 | — | — | US | disclosed |