Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL6944296 | 0.88 | ATM (0.38) | ATMTDP1ALDH1A1HTT | |
| SCHEMBL6949361 | 0.88 | DPP8 (0.39) | ATMTDP1ALDH1A1 | |
| SCHEMBL6945782 | 0.87 | MMP9 (0.42) | KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL6945381 | 0.87 | ATM (0.45) | ATMTDP1CCR5ALDH1A1HTT | |
| SCHEMBL6944292 | 0.87 | CCR5 (0.38) | ATMTDP1CCR5ALDH1A1HTT | |
| SCHEMBL8988351 | 0.87 | DPP8 (0.39) | ATMTDP1 | |
| SCHEMBL6939196 | 0.85 | PREP (0.44) | ALDH1A1HTT | |
| SCHEMBL6945390 | 0.85 | ALDH1A1 (0.37) | ATMTDP1CCR5ALDH1A1HTT | |
| SCHEMBL6944285 | 0.84 | DPP8 (0.45) | ATMTDP1 | |
| SCHEMBL8988171 | 0.84 | ATM (0.35) | ATMTDP1CCR5ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |