SCHEMBL6944038

SCHEMBL6944038

Oc1ccc(C2COc3cc(O)cc(O)c3C2)cc1.Oc1ccc(C2COc3cc(O)cc(O)c3C2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.63
ESR2 Q92731 2/20 0.63
TTR P02766 2/20 0.63
ALOX15 P16050 3/20 0.61
ALOX12 P18054 3/20 0.61
ALOX15B O15296 1/20 0.61
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
CYP3A4 P08684 4/20 0.55
PTGS1 P23219 2/20 0.55
PTGS2 P35354 2/20 0.55
SYNJ2 O15056 1/20 0.55
BACE1 P56817 4/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 3/20 0.46
HSD17B10 Q99714 3/20 0.46
PKM P14618 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
APEX1 P27695 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26078543 1.00 ESR1 (0.63) ESR1ESR2TTRALOX15ALOX12
SCHEMBL29391808 1.00 ESR1 (0.63) ESR1ESR2TTRALOX15ALOX12
SCHEMBL3954415 1.00 ESR1 (0.63) ESR1ESR2TTRALOX15ALOX12
Hydrochloric Acid SCHEMBL4294837 0.98 ESR1 (0.61) ESR1ESR2TTRALOX15ALOX12
SCHEMBL13923917 0.90 ALOX15 (0.53) ESR1ESR2TTRALOX15ALOX12
SCHEMBL2070504 0.89 ESR1 (0.50) ESR1ESR2TTRALOX15ALOX12
Hydrochloric Acid SCHEMBL3957598 0.88 ESR1 (0.49) ESR1ESR2TTRALOX15ALOX12
SCHEMBL5622792 0.85 ESR2 (0.60) ESR1ESR2TTRALOX15ALOX12
SCHEMBL31545141 0.85 ESR2 (0.60) ESR1ESR2TTRALOX15ALOX12
SCHEMBL27944446 0.84 ALOX15 (0.48) ESR1ESR2TTRALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210341-A4 COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF NOVOGEN RES PTY LTD (AU) 2003-06-11 EP disclosed
EP-1210341-A1 COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF Novogen Research Pty. Ltd. (AU) 2002-06-05 EP disclosed
WO-2001017986-A1 COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF NOVOGEN RESEARCH PTY LTD (AU) 2001-03-15 WO disclosed