Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289563 | 0.93 | DPP8 (0.55) | DPP8DPP9KCNJ1KCNH2RECQL | |
| SCHEMBL31095868 | 0.87 | TPSAB1 (0.49) | DPP8DPP9ALDH1A1LMNAMAPT | |
| SCHEMBL6943435 | 0.87 | DPP8 (0.58) | DPP8DPP9KCNJ1KCNH2RECQL | |
| SCHEMBL31095638 | 0.84 | DPP8 (0.48) | DPP8DPP9RECQLALDH1A1LMNA | |
| SCHEMBL8435707 | 0.83 | DPP8 (0.48) | DPP8DPP9KCNJ1KCNH2RECQL | |
| SCHEMBL5873672 | 0.83 | GAA (0.55) | ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL3039451 | 0.83 | KCNJ1 (0.53) | DPP8DPP9KCNJ1KCNH2RECQL | |
| SCHEMBL6944598 | 0.82 | GAA (0.55) | DPP8DPP9KCNJ1KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5724126 | 0.82 | KCNJ1 (0.52) | DPP8DPP9KCNJ1KCNH2RECQL | |
| SCHEMBL7683566 | 0.82 | GAA (0.54) | ALDH1A1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |