Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PREP | P48147 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683566 | 0.99 | GAA (0.54) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11263011 | 0.92 | PREP (0.59) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7159251 | 0.92 | PREP (0.59) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8253758 | 0.89 | PREP (0.60) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8750837 | 0.89 | PREP (0.60) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27758731 | 0.89 | SIGMAR1 (0.48) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8249773 | 0.88 | PREP (0.59) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27795955 | 0.88 | PREP (0.56) | GAAPREPALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30500954 | 0.87 | GAA (0.69) | GAAPREPLMNASMN1; SMN2HTT | |
| SCHEMBL7509784 | 0.85 | PREP (0.54) | GAAPREPALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
| US-7132295-B2 | Isotopically coded affinity markers 3 | BAYER AKTIENGESELLSCHAFT (DE) | 2006-11-07 | — | — | US | disclosed |
| US-20050049406-A1 | Isotopically coded affinity markers 3 | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-03 | — | — | US | disclosed |
| EP-1446665-A2 | ISOTOPICALLY CODED AFFINITY MARKERS 3 | Bayer HealthCare AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003040288-A2 | ISOTOPICALLY CODED AFFINITY MARKERS 3 | BAYER HEALTHCARE AG (DE) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049406-A1 | Isotopically coded affinity markers 3 | IGFBP3, FABP3, LGALS3BP | GAA 4322/4885PREP 1813/4885ALDH1A1 2916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.