Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8439463 | 0.93 | KCNJ1 (0.44) | DPP8DPP9KCNJ1KCNH2ADRB1 | |
| SCHEMBL6944079 | 0.83 | DPP8 (0.52) | DPP8DPP9KCNJ1KCNH2ADRB1 | |
| SCHEMBL8440339 | 0.82 | ALDH1A1 (0.59) | DPP8DPP9ALDH1A1MAPTLMNA | |
| SCHEMBL3039451 | 0.82 | KCNJ1 (0.53) | DPP8DPP9KCNJ1KCNH2ADRB1 | |
| Hydrochloric Acid SCHEMBL5724126 | 0.81 | KCNJ1 (0.52) | DPP8DPP9KCNJ1KCNH2ADRB1 | |
| SCHEMBL6943435 | 0.79 | DPP8 (0.58) | DPP8DPP9KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL27388024 | 0.79 | IDO1 (0.51) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL9661798 | 0.78 | KCNJ1 (0.49) | DPP8DPP9KCNJ1KCNH2ADRB1 | |
| SCHEMBL6943478 | 0.78 | DPP8 (0.61) | DPP8DPP9KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL8435893 | 0.77 | DPP8 (0.41) | DPP8DPP9ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0560613-B1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |