Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27557382 | 0.98 | CYP1A2 (0.46) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Acetic Acid SCHEMBL28085379 | 0.96 | CYP1A2 (0.45) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Bicarbonate SCHEMBL315103 | 0.94 | CYP1A2 (0.49) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Acetic Acid SCHEMBL27557381 | 0.93 | LMNA (0.47) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Acetic Acid SCHEMBL306020 | 0.92 | LMNA (0.49) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Oxalic Acid SCHEMBL1050279 | 0.92 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Bicarbonate SCHEMBL315104 | 0.90 | LMNA (0.50) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Bicarbonate SCHEMBL28141094 | 0.90 | CYP1A2 (0.46) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Bicarbonate SCHEMBL315102 | 0.90 | LMNA (0.50) | CYP1A2ALDH1A1KDM4ETDP1LMNA | |
| Methyl Alcohol SCHEMBL27837342 | 0.89 | KDM4E (0.50) | CYP1A2ALDH1A1KDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254866-B | For reactive adhesive being bonded to the improved method of substrate | 陶氏环球技术公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103254866-A | Improved process for bonding reactive adhesives to substrates | DOW GLOBAL TECHNOLOGIES LLC | 2013-08-21 | — | — | CN | disclosed |
| CN-102149739-B | Improved method for bonding reactive adhesives to substrates | DOW GLOBAL TECHNOLOGIES LLC | 2013-06-19 | — | — | CN | disclosed |
| WO-2003104304-A1 | METHOD FOR MAKING SILOXANE POLYMERS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2003-12-18 | — | — | WO | disclosed |
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | AUSTRALIAN NATIONAL UNIVERSITY, THE (AU) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | CNKSR1, CCNL2, SAAL1 | CHRNB4 4353/4885CHRNA3 3651/4885CYP1A2 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.