Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27557381 | 0.96 | LMNA (0.47) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Bicarbonate SCHEMBL315102 | 0.94 | LMNA (0.50) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Bicarbonate SCHEMBL315104 | 0.94 | LMNA (0.50) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Pyruvate SCHEMBL7965464 | 0.93 | LMNA (0.47) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Oxalic Acid SCHEMBL1050278 | 0.92 | LMNA (0.49) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Acetic Acid SCHEMBL6944290 | 0.92 | CYP1A2 (0.47) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Bicarbonate SCHEMBL7442433 | 0.91 | MEN1 (0.48) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Bicarbonate SCHEMBL28141095 | 0.91 | LMNA (0.48) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Oxalic Acid SCHEMBL1050280 | 0.91 | LMNA (0.48) | LMNAMEN1CYP2D6TSHRKMT2A | |
| Acetic Acid SCHEMBL27557382 | 0.90 | CYP1A2 (0.46) | LMNAMEN1CYP2D6TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292881-B2 | Polyoxyalkylene group-containing organosilicon compound and method for producing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-04-05 | — | — | US | claimed |
| US-20210230371-A1 | METHOD FOR PREPARING ALIPHATIC POLYTHIOETHER | UNIV ZHEJIANG (CN) | 2021-07-29 | — | — | US | claimed |
| CN-110358069-B | Polyester with selenium-containing main chain and preparation method thereof | 浙江大学 | 2020-05-26 | — | — | CN | claimed |
| EP-1464675-B1 | Use of room temperature curable organopolysiloxane compositions for sealing double-glazed panes | SHINETSU CHEMICAL CO (JP) | 2014-07-23 | — | — | EP | claimed |
| US-7553901-B2 | RTV silicone rubber composition for electric and electronic part protection, circuit boards, silver electrodes, and silver chip resistors | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-06-30 | — | — | US | claimed |
| EP-1127916-B1 | Filler/adhesive agent for display units containing a curable silicone composition | DOW CORNING TORAY SILICONE (JP) | 2004-09-22 | — | — | EP | claimed |
| EP-1127916-A1 | Filler/adhesive agent for display units containing a curable silicone composition | Dow Corning Toray Silicone Company, Ltd. (JP) | 2001-08-29 | — | — | EP | claimed |
| US-6268432-B1 | Filler/adhesive agent for display units containing a curable silicone composition | DOW CORNING TORAY SILICONE CO. LTD. (JP) | 2001-07-31 | — | — | US | claimed |
| US-4735971-A | CONTAINING ISOPROPENYL OXYSILYL- AND MERCAPTOALKYL GROUPS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | claimed |
| US-4503226-A | QUATERNARY AMMONIUM CARBOXYLATE CATALYST | OLIN CORPORATION (US) | 1985-03-05 | — | — | US | claimed |
| EP-4745193-A1 | ROOM-TEMPERATURE-CURABLE RESIN COMPOSITION AND ARTICLE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-05-20 | — | — | EP | disclosed |
| US-20260132288-A1 | ORGANOPOLYSILOXANE COMPOUND AND PRODUCTION METHOD THEREOF, AND COMPOSITION CONTAINING SAID COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-05-14 | — | — | US | disclosed |
| EP-4612228-B1 | SILICONE BASED RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE COMPRISING THE SAME | WACKER CHEMIE AG (DE) | 2026-05-06 | — | — | EP | disclosed |
| EP-4623039-B1 | SILICONE BASED RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE COMPRISING THE SAME | WACKER CHEMIE AG (DE) | 2026-04-22 | — | — | EP | disclosed |
| US-20260085187-A1 | SILICONE RESIN COMPOSITION, THERMALLY CONDUCTIVE SHEET, AND ORGANOPOLYSILOXANE | JNC CORPORATION (JP) | 2026-03-26 | — | — | US | disclosed |
| US-4503226-A | QUATERNARY AMMONIUM CARBOXYLATE CATALYST | OLIN CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| US-4460740-A | FLUORINE CONTAINING SURFACTANT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4339563-A | Novel organopolysiloxanes and room temperature curable organopolysiloxane compositions containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1982-07-13 | — | — | US | disclosed |
| US-4323488-A | Method for the preparation of silicone-modified polyoxyalkylene polyethers and room temperature-curable compositions therewith | SHIN-ETSU CHEMICAL COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4302571-A | TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1981-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085187-A1 | SILICONE RESIN COMPOSITION, THERMALLY CONDUCTIVE SHEET, AND ORGANOPOLYSILOXANE | COL2A1, COL1A1, RER1 | CHRNB4 770/4885CHRNA3 1058/4885LMNA 589/4885 |
| US-20260132288-A1 | ORGANOPOLYSILOXANE COMPOUND AND PRODUCTION METHOD THEREOF, AND COMPOSITION CONTAINING SAID COMPOUND | ITGAV, ILK, SMCHD1 | CHRNB4 2661/4885CHRNA3 3006/4885LMNA 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.