Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945022 | 0.81 | SLC6A2 (0.63) | CHRNA7CYP1A2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL10034629 | 0.81 | SLC6A2 (0.63) | CHRNA7CYP1A2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL16606316 | 0.78 | CHRNB2 (0.50) | CHRNA7CHRNB2CHRNA4CYP1A2CYP2D6 | |
| SCHEMBL10586154 | 0.78 | CHRM2 (0.56) | CHRNB2CHRNA4CYP1A2CYP2D6SLC6A2 | |
| SCHEMBL27497409 | 0.77 | CHRNB2 (0.46) | CHRNA7CHRNB2CHRNA4CYP1A2CYP2D6 | |
| SCHEMBL18546642 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL24933229 | 0.76 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNA4CYP1A2CYP2D6 | |
| SCHEMBL29014941 | 0.75 | CYP19A1 (0.47) | CYP1A2CYP2D6ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7927469 | 0.75 | SLC6A2 (0.59) | CHRNA7CHRNB2CHRNA4CYP1A2CYP2D6 | |
| SCHEMBL873444 | 0.74 | SLC6A2 (0.50) | SLC6A2SLC6A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435127-A2 | 3-Substituted pyridines | BASF Aktiengesellschaft (DE) | 1991-07-03 | — | — | EP | claimed |