Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951808 | 0.89 | GAA (0.53) | RNASEH1GAAMAPTSMN1; SMN2KDM5A | |
| SCHEMBL6948961 | 0.89 | RAB9A (0.55) | RAB9ANPC1HDAC6RNASEH1GAA | |
| SCHEMBL6946477 | 0.84 | RAB9A (0.50) | RAB9ANPC1HDAC6RNASEH1NTRK1 | |
| SCHEMBL6942891 | 0.84 | MAPT (0.47) | RAB9ANPC1NTRK1ALDH1A1MAPT | |
| SCHEMBL6948946 | 0.83 | NPC1 (0.46) | RAB9ANPC1HDAC6RNASEH1NTRK1 | |
| SCHEMBL6948426 | 0.82 | NPC1 (0.45) | RAB9ANPC1HDAC6RNASEH1NTRK1 | |
| SCHEMBL6943116 | 0.81 | RAB9A (0.47) | RAB9ANPC1HDAC6RNASEH1NTRK1 | |
| SCHEMBL6949850 | 0.80 | MAPT (0.49) | RAB9ANPC1HDAC6NTRK1GAA | |
| SCHEMBL6374934 | 0.80 | DAGLA (0.44) | RAB9ANPC1HDAC6GAACHRM1 | |
| SCHEMBL6946452 | 0.79 | NPC1 (0.42) | RAB9ANPC1HDAC6RNASEH1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |