Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553897 | 0.90 | GAA (0.54) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL6945368 | 0.89 | RAB9A (0.52) | GAASMN1; SMN2EGFRRNASEH1KDM5A | |
| Hydrochloric Acid SCHEMBL8569715 | 0.89 | GAA (0.53) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL8569705 | 0.87 | GAA (0.51) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL1552358 | 0.87 | RNASEH1 (0.54) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL6950138 | 0.85 | KMT2A (0.49) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL6840255 | 0.81 | KDM5B (0.46) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL6542837 | 0.80 | GAA (0.60) | GAAKMT2APKMSMN1; SMN2TSHR | |
| SCHEMBL6840239 | 0.80 | KDM4C (0.54) | GAAKMT2APKMSMN1; SMN2KDM4A | |
| SCHEMBL9540475 | 0.79 | GAA (0.58) | GAAKMT2APKMTSHREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |