Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948964 | 0.91 | MEN1 (0.52) | MAPTSMN1; SMN2LMNAMEN1HSP90AA1 | |
| SCHEMBL6945413 | 0.89 | LMNA (0.45) | MAPTRAB9ANPC1TSHRCYP1A2 | |
| SCHEMBL6949863 | 0.87 | SCN1A (0.42) | MAPTRAB9ANPC1TSHRCYP1A2 | |
| SCHEMBL6949850 | 0.86 | MAPT (0.49) | MAPTRAB9ANPC1TSHRHSD17B10 | |
| SCHEMBL6945589 | 0.84 | TUBB4A (0.46) | MAPTRAB9ANPC1TSHRCYP1A2 | |
| SCHEMBL6945368 | 0.84 | RAB9A (0.52) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL6948961 | 0.83 | RAB9A (0.55) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6942886 | 0.81 | PARP1 (0.48) | MAPTRAB9ANPC1TSHRCYP1A2 | |
| SCHEMBL6945580 | 0.81 | MAPT (0.45) | MAPTRAB9ANPC1HSD17B10KDM4E | |
| SCHEMBL6948946 | 0.80 | NPC1 (0.46) | MAPTRAB9ANPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |