Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543377 | 0.75 | TAAR1 (0.47) | TAAR1PNMTIDO1MAPTL3MBTL1 | |
| SCHEMBL7953637 | 0.73 | MAPK1 (0.40) | MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6554584 | 0.73 | TUBB4A (0.39) | MAPK1GAASMN1; SMN2 | |
| SCHEMBL7386281 | 0.71 | ALDH1A1 (0.37) | MAPK1SMN1; SMN2 | |
| SCHEMBL7387017 | 0.71 | TAAR1 (0.39) | TAAR1MAPK1ADRA1A | |
| SCHEMBL29023056 | 0.71 | CCR1 (0.34) | MAPK1MAPT | |
| SCHEMBL24822382 | 0.70 | TAAR1 (0.57) | TAAR1PNMTIDO1SMN1; SMN2HPGD | |
| SCHEMBL1569511 | 0.69 | ESR1 (0.39) | MAPK1MAPTGAASMN1; SMN2ABCB1 | |
| SCHEMBL7389699 | 0.69 | HTR1B (0.43) | HTR2A | |
| SCHEMBL7387972 | 0.69 | MAPT (0.41) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218739-A4 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-04 | — | — | EP | claimed |
| EP-1218739-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023887-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | claimed |