Hydrazine

Hydrazine

SCHEMBL6945698

CS(=O)(=O)O.NN

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of Hydrazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL5543279 1.00 CA2 (0.50)
Hydroxyamine SCHEMBL5552814 0.90
Methylamine SCHEMBL330884 0.90
SCHEMBL246838 0.89 CA2 (0.58)
SCHEMBL128169 0.89
SCHEMBL15109974 0.89
SCHEMBL105 0.89
SCHEMBL8596055 0.89 CA2 (0.58)
SCHEMBL25599 0.89 CA2 (0.58)
Hydroxyamine SCHEMBL788269 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113614114-B Method for quantifying oligosaccharide preparations 帝斯曼知识产权资产管理有限公司 2023-08-29 CN disclosed
CN-109503418-B Preparation process of methylhydrazine 河北合佳医药科技集团股份有限公司 2021-06-08 CN disclosed
EP-0967210-B1 PROCESS FOR PREPARING BIOLOGICALLY ACTIVE DERIVATIVES OF 1,2,4-TRIAZOL AND INTERMEDIARIES USEFUL IN THIS PROCESS KRKA TOVARNA ZDRAVIL D D NOVO (SI) 2003-06-04 EP disclosed
EP-0967210-A1 PROCESS FOR PREPARING BIOLOGICALLY ACTIVE DERIVATIVES OF 1,2,4-TRIAZOL AND INTERMEDIARIES USEFUL IN THIS PROCESS CENTRO GENESIS PARA LA INVESTIGACION, S.L. (ES) 1999-12-29 EP disclosed