Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945772 | 0.92 | ALOX15 (0.68) | ALOX15MTORRAB9ACACNA1BMEN1 | |
| SCHEMBL6948648 | 0.87 | CYP1A2 (0.62) | ALOX15MTORRAB9AMEN1KMT2A | |
| SCHEMBL6945817 | 0.87 | ALOX15 (0.51) | ALOX15MTORCACNA1BMEN1KMT2A | |
| SCHEMBL6950016 | 0.87 | ALOX15 (0.50) | ALOX15CACNA1BMAPTKDM4EADORA3 | |
| SCHEMBL6944706 | 0.80 | ALOX15 (0.64) | ALOX15MTORMEN1KMT2ACYP1A2 | |
| SCHEMBL7881070 | 0.80 | KDM4E (0.54) | MTORRAB9ACACNA1BMEN1KMT2A | |
| SCHEMBL6945482 | 0.80 | CACNA1B (0.48) | ALOX15RAB9ACACNA1BMEN1KMT2A | |
| SCHEMBL6949620 | 0.80 | CACNA1C (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7266477 | 0.79 | KDM4E (0.56) | CACNA1BMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6949599 | 0.78 | ALOX15 (0.61) | ALOX15MTORMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |