Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942912 | 0.93 | PPARA (0.62) | PPARAPPARGGAAALDH1A1MAPK1 | |
| SCHEMBL6942909 | 0.93 | PPARA (0.62) | PPARAPPARGGAAALDH1A1MAPK1 | |
| SCHEMBL10580231 | 0.88 | PPARA (0.50) | PPARAPPARGGAAALDH1A1MAPK1 | |
| SCHEMBL11774358 | 0.84 | PPARA (0.56) | PPARAPPARGACEHDAC1HDAC2 | |
| SCHEMBL6944182 | 0.83 | ALDH1A1 (0.47) | PPARAPPARGCACNA1BGAAALDH1A1 | |
| SCHEMBL6944179 | 0.83 | ALDH1A1 (0.47) | PPARAPPARGCACNA1BGAAALDH1A1 | |
| SCHEMBL9299418 | 0.80 | PPARA (0.74) | PPARAPPARGACEATM | |
| SCHEMBL9299417 | 0.80 | PPARA (0.74) | PPARAPPARGACEATM | |
| SCHEMBL9840640 | 0.80 | GAA (0.51) | GAAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3869417 | 0.79 | PPARG (0.74) | PPARAPPARGALDH1A1ACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |