Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944182 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTCACNA1BKMT2A | |
| SCHEMBL6944304 | 0.85 | CACNA1B (0.39) | ALDH1A1SMN1; SMN2MAPTCACNA1BP2RX7 | |
| SCHEMBL6944300 | 0.85 | CACNA1B (0.39) | ALDH1A1SMN1; SMN2MAPTCACNA1BP2RX7 | |
| SCHEMBL6945857 | 0.83 | PPARA (0.53) | ALDH1A1MAPTCACNA1BKMT2AGAA | |
| SCHEMBL6940993 | 0.80 | HDAC1 (0.38) | KMT2AP2RX7CTSLPPARGPPARA | |
| SCHEMBL6940996 | 0.80 | HDAC1 (0.38) | KMT2AP2RX7CTSLPPARGPPARA | |
| SCHEMBL6944598 | 0.80 | GAA (0.55) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL6942909 | 0.79 | PPARA (0.62) | ALDH1A1KMT2AGAAMAPK1L3MBTL1 | |
| SCHEMBL6942912 | 0.79 | PPARA (0.62) | ALDH1A1KMT2AGAAMAPK1L3MBTL1 | |
| SCHEMBL6944839 | 0.77 | DPP8 (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |