SCHEMBL112101

SCHEMBL112101

O=S(=O)(O)c1ccc(/N=N/c2ccc(O)cc2O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.69
MAPT P10636 3/20 0.61
MEN1 O00255 2/20 0.61
ALDH1A1 P00352 2/20 0.61
KMT2A Q03164 2/20 0.61
POLB P06746 2/20 0.61
LMNA P02545 2/20 0.61
HTT P42858 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
RPS6KA3 P51812 1/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
NSD2 O96028 2/20 0.57
MMP14 P50281 2/20 0.57
CASP6 P55212 2/20 0.57
CYP2D6 P10635 1/20 0.54
ATIC P31939 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112102 1.00 EGFR (0.69) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL29378452 1.00 EGFR (0.69) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL144370 0.98 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL144372 0.98 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL29555012 0.86 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL94484 0.86 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL144371 0.86 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL5364165 0.85 RPS6KA3 (0.62) EGFRMAPTMEN1KMT2APOLB
SCHEMBL9099069 0.84 RPS6KA3 (0.55) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL4842755 0.84 RPS6KA3 (0.55) EGFRMAPTMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11940387-B2 Portable liquid analyzer VERITEQUE USA, INC. (US) 2024-03-26 US claimed
US-20200371038-A1 PORTABLE LIQUID ANALYZER S2 DETECTION (NEVADA) INC. 2020-11-26 US claimed
EP-2368558-A1 Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates Mdc Max-Delbrück-Centrum Für Molekulare Medizin Berlin - Buch (DE) 2011-09-28 EP claimed
EP-0696269-B1 PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES MONSANTO CO (US) 1999-06-30 EP claimed
EP-0641313-B1 PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES MONSANTO CO (US) 1997-01-22 EP claimed
US-20230131243-A1 METHODS OF ATTENUATING AN IMMUNE RESPONSE BY INHIBITION OF BFL1 CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-04-27 US disclosed
US-20230131243-A1 METHODS OF ATTENUATING AN IMMUNE RESPONSE BY INHIBITION OF BFL1 CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-04-27 US disclosed
US-11541073-B2 Methods of attenuating an immune response by inhibition of BFL1 CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-01-03 US disclosed
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances CLARIANT INTERNATIONAL LTD. (CH) 2021-09-07 US disclosed
US-20210171883-A1 ANTIVIRAL WIPER FUJIFILM CORPORATION (JP) 2021-06-10 US disclosed
US-20210113604-A1 METHODS OF TREATMENT BY INHIBITION OF BFL1 CHILDREN'S HOSPITAL MEDICAL CENTER 2021-04-22 US disclosed
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group CLARIANT INTERNATIONAL LTD. (CH) 2019-09-10 US disclosed
EP-1400574-A1 Colour changing paint Akzo Nobel Decorative Coatings Ltd. (GB) 2004-03-24 EP disclosed
EP-1374837-A1 Aerosol foam for treating the hair Wella Aktiengesellschaft (DE) 2004-01-02 EP disclosed
EP-1362576-A2 Non aerosol and aerosol hair mousse Wella Aktiengesellschaft (DE) 2003-11-19 EP disclosed
EP-1358929-A2 Method for the production of hair or skin cosmetic products using apparatus with microstructures Wella Aktiengesellschaft (DE) 2003-11-05 EP disclosed
US-6620420-B2 Cosmetic or dermatological application BEIERSDORF AG (DE) 2003-09-16 US disclosed
CN-1406577-A Cosmetic W/O emulsion and agents for skin containing amino substituted hydroxy diphenyl ketone BASF AG (DE) 2003-04-02 CN disclosed
CN-1406576-A Oil in water low emulsifier or non-emulsifier system containing stabilizer and amiho substituted hydroxy diphenyl ketone BASF AG (DE) 2003-04-02 CN disclosed
US-4084983-A ALUMINUM FLAKES ON A COATING OF ALUMINUM HYDROXIDE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances GPX4, LPO, CAT EGFR 3601/4885MAPT 1729/4885MEN1 3224/4885
US-20230131243-A1 METHODS OF ATTENUATING AN IMMUNE RESPONSE BY INHIBITION OF BFL1 CD74, IRF3, IRF2BP2 EGFR 3604/4885MAPT 4608/4885MEN1 4808/4885
US-20210171883-A1 ANTIVIRAL WIPER CGAS, PRKX, PDE4C EGFR 4834/4885MAPT 4519/4885MEN1 3305/4885
US-20210113604-A1 METHODS OF TREATMENT BY INHIBITION OF BFL1 DNASE1L3, ILF2, NCF1 EGFR 3315/4885MAPT 4347/4885MEN1 4786/4885
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group ADH5, ADH1A, ADH1C EGFR 1504/4885MAPT 1822/4885MEN1 3537/4885
US-11541073-B2 Methods of attenuating an immune response by inhibition of BFL1 CD74, IRF3, IRF2BP2 EGFR 3604/4885MAPT 4608/4885MEN1 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.