Sugi Predict

Sugi Predict / Compounds / SCHEMBL144372

SCHEMBL144372

SCHEMBL144372

O=S(=O)(O)c1ccc(N=Nc2ccc(O)cc2O)cc1.[NaH]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.67
▸ MAPT P10636 3/20 0.60
▸ MEN1 O00255 2/20 0.60
▸ ALDH1A1 P00352 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ LMNA P02545 2/20 0.60
▸ HTT P42858 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.60
▸ RPS6KA3 P51812 1/20 0.60
▸ NPC1 O15118 2/20 0.59
▸ RAB9A P51151 2/20 0.59
▸ NSD2 O96028 2/20 0.56
▸ MMP14 P50281 2/20 0.56
▸ CASP6 P55212 2/20 0.56
▸ CYP2D6 P10635 1/20 0.53
▸ ATIC P31939 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144370 1.00 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL112101 0.98 EGFR (0.69) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL112102 0.98 EGFR (0.69) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL29378452 0.98 EGFR (0.69) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL94484 0.84 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL29555012 0.84 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL144371 0.84 EGFR (0.67) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL5364165 0.83 RPS6KA3 (0.62) EGFRMAPTMEN1KMT2APOLB
SCHEMBL4842755 0.83 RPS6KA3 (0.55) EGFRMAPTMEN1ALDH1A1KMT2A
SCHEMBL9099069 0.83 RPS6KA3 (0.55) EGFRMAPTMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 — — EP claimed
US-10259946-B1 Sealing agents, methods of making and uses thereof James Hardie Technology Limited (IE) 2019-04-16 — — US disclosed
US-9693937-B2 Foil applicator HENKEL AG & CO. KGAA (DE) 2017-07-04 — — US disclosed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 — — US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 — — US disclosed
US-20150174019-A1 FOIL APPLICATOR HENKEL AG & CO. KGAA (DE) 2015-06-25 — — US disclosed
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2014-10-09 — — US disclosed
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2014-10-02 — — US disclosed
US-8632612-B2 Compositions for dyeing keratin fibers SEGETIS, INC. (US) 2014-01-21 — — US disclosed
EP-2613760-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS Segetis, Inc. (US) 2013-07-17 — — EP disclosed
EP-1317917-A1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2003-06-11 — — EP disclosed
US-6558433-B2 Oxidation hair dye WELLA AG (DE) 2003-05-06 — — US disclosed
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same Wella GmbH (DE) 2003-03-06 — — US disclosed
US-20020189031-A1 Use of salts for improving the absorption qualities of anionic direct dyes WELLA AKTIENGESELLSCHAFT (DE) 2002-12-19 — — US disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 — — US disclosed
US-20020170125-A1 Bridged diaminopyrazole compounds and dye compositions containing same HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2002-11-21 — — US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 — — US disclosed
US-6379400-B1 DYEING FIBERS, SOLVENT OF WATER OR ALCOHOL AND NITROANILINE DYE WELLA AKTIENGESELLSCHAFT (DE) 2002-04-30 — — US disclosed
US-6231622-B1 MIXTURES; BLUE COLOR WELLA AKTIENGESELLSCHAFT (DE) 2001-05-15 — — US disclosed
US-6106579-A MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2000-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES KRT18, DSG1, PKN1 EGFR 2101/4885MAPT 546/4885MEN1 4097/4885
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, PKN3, IK EGFR 606/4885MAPT 2581/4885MEN1 4795/4885
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same KRT18, SCNN1B, DDAH1 EGFR 1252/4885MAPT 2639/4885MEN1 1222/4885
US-20020170125-A1 Bridged diaminopyrazole compounds and dye compositions containing same ALK, DDC, CBR1 EGFR 634/4885MAPT 4236/4885MEN1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.