Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948248 | 0.87 | RAB9A (0.48) | CREBBPBRD4HDAC6NPC1RAB9A | |
| SCHEMBL6947019 | 0.83 | MAPT (0.44) | CREBBPBRD4MMP2HDAC6NPC1 | |
| SCHEMBL6946613 | 0.81 | MMP2 (0.50) | MMP2HDAC6NPC1RAB9APLA2G2A | |
| SCHEMBL24744902 | 0.76 | PARP1 (0.42) | GAA | |
| SCHEMBL6953197 | 0.76 | MMP2 (0.44) | CREBBPBRD4MMP2HDAC6NPC1 | |
| SCHEMBL6953199 | 0.74 | MMP2 (0.45) | CREBBPBRD4MMP2HDAC6NPC1 | |
| SCHEMBL6954309 | 0.73 | MAPT (0.43) | CREBBPBRD4MMP2HDAC6NPC1 | |
| SCHEMBL11563800 | 0.72 | BRD4 (0.43) | CREBBPBRD4MMP2HDAC6NPC1 | |
| SCHEMBL6948942 | 0.72 | BRD4 (0.50) | CREBBPBRD4MMP2HDAC6NPC1 | |
| Hydrochloric Acid SCHEMBL6953955 | 0.72 | MMP2 (0.45) | CREBBPBRD4MMP2HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |