Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032817 | 0.83 | HTR2A (0.62) | MEN1KMT2AATMBCHEKDM4E | |
| SCHEMBL10032816 | 0.76 | MEN1 (0.85) | MEN1KMT2AATMBCHECA1 | |
| SCHEMBL12131075 | 0.76 | MEN1 (0.85) | MEN1KMT2AATMBCHECA1 | |
| SCHEMBL7503765 | 0.76 | HTR2A (0.59) | MEN1KMT2AATMBCHEHTR2A | |
| SCHEMBL6946746 | 0.75 | NPC1 (0.58) | MEN1KMT2ASLC6A5KDM4EMTNR1A | |
| SCHEMBL10032820 | 0.75 | BCHE (0.64) | MEN1KMT2AATMBCHEKDM4E | |
| SCHEMBL6806326 | 0.75 | HTR2A (0.62) | MEN1KMT2AATMBCHEHTR2A | |
| Perchlorate SCHEMBL7325314 | 0.74 | HTR2A (0.47) | MEN1KMT2AATMBCHECA1 | |
| SCHEMBL4614753 | 0.74 | MEN1 (0.71) | MEN1KMT2AATMBCHEKDM4E | |
| SCHEMBL29194688 | 0.74 | BCHE (0.80) | MEN1KMT2AATMBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |