Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320887 | 0.77 | MEN1 (0.65) | MEN1KMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL7323259 | 0.76 | SMN1; SMN2 (0.56) | HTR2AMEN1KMT2AATMMAPT | |
| SCHEMBL7325319 | 0.76 | SLC2A1 (0.41) | MEN1KMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL6946739 | 0.74 | MEN1 (0.58) | HTR2AMEN1KMT2AATMMTNR1A | |
| SCHEMBL4614753 | 0.73 | MEN1 (0.71) | MEN1KMT2AATMBCHEPLAAT3 | |
| SCHEMBL9517424 | 0.72 | CHRM2 (0.70) | MEN1KMT2ABCHESLC2A1GAA | |
| SCHEMBL8230324 | 0.72 | HTR2A (0.54) | HTR2AATMMTNR1AMTNR1BTAAR1 | |
| SCHEMBL7503765 | 0.72 | HTR2A (0.59) | HTR2AMEN1KMT2AATMMTNR1A | |
| Bromide SCHEMBL9649046 | 0.71 | CHRM2 (0.68) | MEN1KMT2ABCHESLC2A1GAA | |
| SCHEMBL10032817 | 0.71 | HTR2A (0.62) | HTR2AMEN1KMT2AATMBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661635-A | ANTIARRHYTHMIA AGENTS | MCNEILAB, INC. (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0146271-A2 | Aralykyl (arylethynyl) aralkyl amines for use as vasodilators and antihypertensives | McNeilab, Inc. (US) | 1985-06-26 | — | — | EP | disclosed |