Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 10/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950494 | 0.92 | ITGB3 (0.51) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL4924109 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL6947579 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL7403231 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL6946962 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL9390838 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL6948963 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL6950480 | 0.77 | ITGB3 (0.57) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL7384981 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BSUCNR1ITGAVITGB5 | |
| SCHEMBL7388220 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BSUCNR1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | claimed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | claimed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | claimed |
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | disclosed |