Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.51 |
| ▸ | ITGAV | P06756 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924109 | 0.99 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6950494 | 0.96 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6946972 | 0.89 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL7403231 | 0.85 | ITGB3 (0.46) | ITGB3ITGAVITGA2BSUCNR1TBXAS1 | |
| SCHEMBL6946884 | 0.85 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL4924076 | 0.84 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6948963 | 0.83 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6954777 | 0.81 | FOLH1 (0.47) | TBXAS1MAPTCYP3A4PTAFR | |
| SCHEMBL7766464 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6950480 | 0.81 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | claimed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | claimed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | claimed |
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5602155-A | GUANIDINO ALKYL AND PYRIDINE CARBOXYLATE SUBSTITUTED AMIDES | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996023771-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-08 | — | — | WO | disclosed |