Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 11/20 | 0.53 |
| ▸ | CTSS | P25774 | 11/20 | 0.53 |
| ▸ | CTSK | P43235 | 8/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660684 | 0.88 | HTT (0.52) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL10556998 | 0.88 | HTT (0.52) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL24853554 | 0.86 | CTSS (0.60) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL29249016 | 0.86 | CTSS (0.60) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL8728480 | 0.86 | CTSL (0.52) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL7418478 | 0.86 | TACR1 (0.55) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL6312394 | 0.85 | CTSL (0.65) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL6318841 | 0.85 | CTSL (0.65) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL392814 | 0.85 | CTSL (0.65) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL16357709 | 0.84 | CTSS (0.67) | TACR1CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |
| US-5747499-A | CYCLOPENTAQUINAZOLINE COMPOUNDS CYCLOPENTAQUINAZOLINE COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |