Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 13/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.39 |
| ▸ | NQO2 | P16083 | 9/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129512 | 0.86 | MTNR1A (0.54) | HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL6954008 | 0.72 | HTR6 (0.47) | HTR6 | |
| SCHEMBL13947543 | 0.71 | HTR6 (0.55) | HTR6 | |
| SCHEMBL13240022 | 0.71 | HTR6 (0.55) | HTR6 | |
| SCHEMBL13947710 | 0.71 | HTR6 (0.60) | HTR6 | |
| SCHEMBL13964619 | 0.70 | HTR6 (0.62) | HTR6 | |
| SCHEMBL5502315 | 0.70 | HTR6 (1.00) | HTR6 | |
| SCHEMBL14262595 | 0.69 | HTR6 (0.58) | HTR6 | |
| SCHEMBL13946960 | 0.69 | HTR6 (0.66) | HTR6 | |
| SCHEMBL13368569 | 0.69 | HTR6 (0.71) | HTR6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851855-B9 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-0851855-B1 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2002-06-05 | — | — | EP | claimed |
| US-6140372-A | N-(2-(2-ACETYL-7-METHOXYNAPHTH-1-YL)ETHYL)ACETAMIDE; SEDATIVES; MELATONIN DISORDERS; DRUGS; COSMETICS; ANTIDEPRESSANTS; PSYCHIATRIC DISORDERS, E.G., STRESS, ANXIOLYTIC AGENTS, INSOMNIA, SCHIZOPHRENIA, PSYCHOSIS | CEMAF AND LABORATORIES BESINS ISOVESCO S.A. (FR) | 2000-10-31 | — | — | US | disclosed |
| US-6004991-A | COMPOUNDS FOR COSMETICS WITH ENANTIOMORPHS | CEMAF AND LABORATOIRES BESINS ISCOVESCO S.A. (FR) | 1999-12-21 | — | — | US | disclosed |