Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.73 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.73 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.71 |
| ▸ | LTA4H | P09960 | 12/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224640 | 0.98 | PSMB1 (0.76) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL14287622 | 0.90 | HRH3 (0.77) | HRH3 | |
| SCHEMBL15876472 | 0.87 | LTA4H (0.68) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL15876475 | 0.87 | LTA4H (0.72) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL23291141 | 0.85 | PSMB1 (0.71) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL113404 | 0.85 | LTA4H (0.69) | HRH3LTA4H | |
| SCHEMBL15876462 | 0.85 | PSMB1 (0.71) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL4283657 | 0.84 | KDM4E (0.74) | LTA4H | |
| SCHEMBL23291204 | 0.83 | LTA4H (0.68) | PSMB1PSMB5PSMB2HRH3LTA4H | |
| SCHEMBL4286569 | 0.83 | KDM4E (0.72) | PSMB1PSMB5PSMB2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019047-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-11-05 | — | — | EP | disclosed |
| US-6541499-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| EP-1019047-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1019047-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998048800-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0306827-B1 | AMIDE COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR ACTIVATING GASTRIC MOTOR FUNCTION CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-4983633-A | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0306827-A1 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-03-15 | — | — | EP | disclosed |