Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydrophenylalanine Methyl Ester SCHEMBL6947585 | 1.00 | MEN1 (0.49) | MEN1KMT2AAKR1C3MCL1RECQL | |
| Dehydrophenylalanine Methyl Ester SCHEMBL27965511 | 0.98 | MEN1 (0.47) | MEN1KMT2AAKR1C3MCL1RECQL | |
| Dehydrophenylalanine Methyl Ester SCHEMBL27534487 | 0.87 | MEN1 (0.46) | MEN1KMT2AAKR1C3RECQLALDH1A1 | |
| SCHEMBL10809742 | 0.86 | MEN1 (0.44) | MEN1KMT2AAKR1C3MCL1RECQL | |
| SCHEMBL8366934 | 0.82 | NPSR1 (0.47) | NPSR1ALDH1A1 | |
| SCHEMBL77732 | 0.82 | MEN1 (0.63) | MEN1KMT2AAKR1C3MAPTNPSR1 | |
| SCHEMBL5614482 | 0.80 | KMT2A (0.45) | MEN1KMT2AAKR1C3MCL1RECQL | |
| SCHEMBL12449471 | 0.80 | MEN1 (0.72) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL11136280 | 0.80 | MEN1 (0.72) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL1221498 | 0.80 | MEN1 (0.52) | MEN1KMT2AAKR1C3RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098160-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | ENANTIA, S.L. (ES) | 2011-08-18 | — | — | WO | disclosed |
| EP-1709054-B1 | METALLOCENE-BASED CHIRAL PHOSPHINE OR ARSINE LIGANDS | PHOENIX CHEMICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1335898-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | Prolifix Limited (GB) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |