Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydrophenylalanine Methyl Ester SCHEMBL6947584 | 1.00 | MEN1 (0.49) | MEN1KMT2AAKR1C3MCL1RECQL | |
| Dehydrophenylalanine Methyl Ester SCHEMBL27965511 | 0.98 | MEN1 (0.47) | MEN1KMT2AAKR1C3MCL1RECQL | |
| Dehydrophenylalanine Methyl Ester SCHEMBL27534487 | 0.87 | MEN1 (0.46) | MEN1KMT2AAKR1C3RECQLALDH1A1 | |
| SCHEMBL10809742 | 0.86 | MEN1 (0.44) | MEN1KMT2AAKR1C3MCL1RECQL | |
| SCHEMBL8366934 | 0.82 | NPSR1 (0.47) | NPSR1ALDH1A1 | |
| SCHEMBL77732 | 0.82 | MEN1 (0.63) | MEN1KMT2AAKR1C3MAPTNPSR1 | |
| SCHEMBL5614482 | 0.80 | KMT2A (0.45) | MEN1KMT2AAKR1C3MCL1RECQL | |
| SCHEMBL12449471 | 0.80 | MEN1 (0.72) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL11136280 | 0.80 | MEN1 (0.72) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL1221498 | 0.80 | MEN1 (0.52) | MEN1KMT2AAKR1C3RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102586798-B | Method for synthesizing 2-(N-benzyl)methyl acetamido methylpropionate | UNIV EAST CHINA NORMAL | 2014-07-16 | — | — | CN | claimed |
| CN-102586798-A | Method for synthesizing 2-(N-benzyl)methyl acetamido methylpropionate | UNIV EAST CHINA NORMAL | 2012-07-18 | — | — | CN | claimed |
| CN-103936752-A | Isatin histone deacetylase inhibitors as well as preparation method and applications thereof | WEIFANG BOCHUANG INTERNAT BIOMEDICAL RES INST | 2014-07-23 | — | — | CN | disclosed |
| CN-102586798-B | Method for synthesizing 2-(N-benzyl)methyl acetamido methylpropionate | UNIV EAST CHINA NORMAL | 2014-07-16 | — | — | CN | disclosed |
| CN-102659634-B | Synthetic method for 2-(N-4-fluorobenzyl) methoxy-acetyl-amino methyl isobutyrate | UNIV EAST CHINA NORMAL | 2013-11-27 | — | — | CN | disclosed |
| CN-102869648-A | Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines | WESTFAELISHE WILHELMS U MUENSTER | 2013-01-09 | — | — | CN | disclosed |
| CN-102659634-A | Synthetic method for 2-(N-4-fluorobenzyl) methoxy-acetyl-amino methyl isobutyrate | UNIV EAST CHINA NORMAL | 2012-09-12 | — | — | CN | disclosed |
| CN-102586798-A | Method for synthesizing 2-(N-benzyl)methyl acetamido methylpropionate | UNIV EAST CHINA NORMAL | 2012-07-18 | — | — | CN | disclosed |
| CN-1982299-A | Benzoxasine and benzothiasine derivatives and pharmaceutical composition containing the same | REDDY RES FOUNDATION (IN) | 2007-06-20 | — | — | CN | disclosed |
| CN-1596249-A | benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2005-03-16 | — | — | CN | disclosed |
| CN-1589258-A | Novel beta -phenyl- alpha -oxysubstituted propionic derivatives: process for their preparation and their use in the preparation of pharmaceutically important compounds | REDDY S LAB LTD (IN) | 2005-03-02 | — | — | CN | disclosed |
| EP-1335898-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | Prolifix Limited (GB) | 2003-08-20 | — | — | EP | disclosed |
| CN-1098278-C | Cinnamic acid derivative | SEIKAGAKU KOGYO CO LTD (JP) | 2003-01-08 | — | — | CN | disclosed |
| CN-1090637-C | Crosslinked cinnamic acid hyaluronic acid derivatives and process for producing the same | SEIKAGAKU KOGYO CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |
| CN-1245812-A | Cinnamic acid derivative | SEIKAGAKU KOGYO CO LTD (JP) | 2000-03-01 | — | — | CN | disclosed |
| CN-1133834-A | cinnamic acid derivatives | SEIKAGAKU KOGYO CO LTD (JP) | 1996-10-23 | — | — | CN | disclosed |