Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949624 | 0.93 | KDM4E (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6949149 | 0.85 | PYGM (0.51) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6952272 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6945804 | 0.82 | GAA (0.44) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6945824 | 0.81 | NR3C2 (0.44) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL9034113 | 0.77 | CACNA1C (0.48) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6950023 | 0.76 | LMNA (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6949620 | 0.75 | CACNA1C (0.55) | MAPTCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6953545 | 0.73 | PYGM (0.49) | TDP1RECQLNR3C2PYGLPYGM | |
| SCHEMBL6945806 | 0.72 | CACNA1C (0.59) | MAPTCACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |