Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 17/20 | 0.53 |
| ▸ | PYGL | P06737 | 16/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953545 | 0.92 | PYGM (0.49) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL6950023 | 0.90 | LMNA (0.46) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL6949414 | 0.88 | PYGM (0.49) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL6953114 | 0.88 | NR3C2 (0.49) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL6949149 | 0.85 | PYGM (0.51) | PYGMPYGLNR3C2 | |
| SCHEMBL6951538 | 0.85 | PYGM (0.51) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL6952044 | 0.84 | PYGM (0.50) | PYGMPYGLNR3C2 | |
| SCHEMBL6945824 | 0.81 | NR3C2 (0.44) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL9233347 | 0.81 | PYGM (0.47) | PYGMPYGLNR3C2KMT2A | |
| SCHEMBL7307972 | 0.80 | PYGM (0.51) | PYGMPYGLNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-0657432-A1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |