Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 9/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250573 | 1.00 | CYP2C19 (0.48) | CYP2C19HSP90AA1HSPA5CYP2C9HIF1A | |
| SCHEMBL11773434 | 0.86 | CYP2C19 (0.47) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP2D6 | |
| SCHEMBL14702177 | 0.85 | CYP2C19 (0.46) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP2D6 | |
| SCHEMBL11443946 | 0.85 | CYP2C19 (0.46) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11492917 | 0.83 | CYP2C19 (0.44) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP2D6 | |
| SCHEMBL6321695 | 0.83 | GABRA1 (0.52) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP1A2 | |
| SCHEMBL10947681 | 0.82 | CYP3A4 (0.54) | CYP2C19HSP90AA1HSPA5CYP2C9HIF1A | |
| SCHEMBL29065613 | 0.81 | GABRA1 (0.50) | CYP2C19CYP2C9HIF1ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11242368 | 0.80 | CYP2C19 (0.42) | CYP2C19CYP2C9HIF1ACYP2D6CYP1A2 | |
| SCHEMBL70807 | 0.79 | CYP2C19 (0.53) | CYP2C19HSPA5CYP2C9HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2023-05-18 | — | — | US | claimed |
| EP-4125833-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | Orpha Biotech S.r.l. (IT) | 2023-02-08 | — | — | EP | claimed |
| WO-2021198844-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2021-10-07 | — | — | WO | claimed |
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2023-05-18 | — | — | US | disclosed |
| EP-4125833-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | Orpha Biotech S.r.l. (IT) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021198844-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2021-10-07 | — | — | WO | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | CYP2C19 3009/4885HSP90AA1 106/4885HSPA5 133/4885 |
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | FPR3, FPR1, PLAUR | CYP2C19 3289/4885HSP90AA1 2925/4885HSPA5 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.