Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639064 | 0.83 | MAPT (0.74) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL9581525 | 0.81 | XDH (0.42) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL9581353 | 0.81 | XDH (0.42) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL667904 | 0.79 | ALDH1A1 (0.47) | MAPTKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL7404009 | 0.79 | XDH (0.53) | MAPTKDM4EMEN1KMT2AXDH | |
| SCHEMBL11377025 | 0.78 | MAPT (0.68) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL4614355 | 0.78 | MAPT (0.50) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL416580 | 0.78 | MAPT (0.68) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL404515 | 0.78 | ALDH1A1 (0.48) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL2258930 | 0.78 | VCAM1 (0.58) | MAPTMAPK1KDM4EMEN1G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |